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Alpha-Lipoic Acid (ALA)

       ALA is an organosulfur compound that has shown efficacy for nerve damage from diabetes with poor blood sugar control, hyperlipidemia, and obesity. ALA is made inside mitochondria where it has essential roles in enzymes involved in mitochondrial dehydrogenase reactions.


       ALA also activates AMPK which regulates cellular energy homeostasis. ALA also has antioxidant activity that protects membranes by interacting with vitamin C and glutathione, which may in turn recycle vitamin E.


       ALA is both water an fat soluble, which allows it to work in every cell of the body. The human body only produces ALA in small quantities. ALA is found in animal products like red meat and organ meats, and vegetables such as broccoli, tomatoes, spinach, and brussels. However, the quantities of ALA found in small is relatively low, and supplements can pack up to 1,000 times more ALA than food sources.



Reference:
Improves mitochondrial function[1] [5]
Antioxidant[4] [9] [15]
AMPK activator[16]
Anti-inflammatory[4] [14]
Anti-diabetes[3] [7] [8] [13] [17]
Promotes heart health[2] [4] [15]
Boosts weight loss[5] [6]
Lowers blood pressure[2]
Improves skin health[10]
Neuroprotective[11] [12] [13]
Lowers cholesterol[17]