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Pyrroloquinoline Quinone (PQQ)

       PQQ is a vitamin-like compound that cannot be produced by the body, so is mainly acquired through diet. PQQ has growth-promoting activity, anti-diabetic effect, anti-oxidative action, and neuroprotective function. It supports development of mitochondria, and improves mitochondrial efficiency from the declines associated with aging. PQQ also promotes cardiovascular health by protecting the heart against damage caused by stress. PQQ is a very powerful antioxidant that is around 100 times more potent than vitamin C. It also has a special ability to promote the creation of new mitochondria in the body.

       PQQ is very water soluble and therefore easily absorbed into the body. Supplementing with PQQ in PQQ-deficient individuals improves blood sugar levels and lipid levels through PQQ's role in the insulin signaling pathway. PQQ also participates in the energy transfer within the mitochondria, similar to Coenzyme Q10, and therefore has great synergy with CoQ10. PQQ stimulates nerve growth factor (NGF) synthesis and secretion required for the development and maintenance of certain neurons, as well as reducing oxidative stress associated with neurodegeneration.

       PQQ is found in many foods like spinach, kiwi, green tea, soybeans, cocoa, and human milk. The amount of PQQ in food is minimal, estimated from 0.1-1mg on an usual diet.

Primary Benefits:Reference:
Boosts mitochondrial function and biogenesis[1] [4] [11] [12]
Powerful antioxidant[11] [12] [13] [14]
AMPK activator[7]
mTOR inhibitor[5]
Sirtuin activator[4] [6]
Improves brain health[2] [3] [11] [18]
Anti-diabetes[2] [11]
Anti-inflammatory[9] [10] [11] [12] [15]
Promotes heart health[16]
Lowers cholesterol[17]